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Biomarkers identified in collegiate athletes that could help predict time needed to recover from concussion

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Thursday, August 27, 2020


A collaborative study done by experts from the National Institutes of Overall health, Division of Protection (DOD), and numerous academic institutions has identified blood biomarkers that could assist to forecast which athletes want extra time to recover from a athletics relevant concussion. This collaboration, recognised as the Concussion Evaluation, Investigate, and Education and learning (Treatment) consortium, is supported, in element, by DOD and the National Collegiate Athletic Affiliation (NCAA).

In this study, done at several web-sites across the U.S., 127 male and female collegiate athletes who experienced sustained a athletics-relevant concussion ended up tested at several time points: soon after personal injury, when their symptoms solved, and one particular week after returning to participate in. Just about every athlete experienced also been through preseason, baseline screening.

Employing an ultrasensitive assay that can detect moment quantities of protein, the scientists tested blood serum from these athletes and identified two blood proteins that ended up affiliated with the length of time necessary by the athletes to return to participate in. Amounts of these two proteins, tau protein and glial fibrillary acidic protein (GFAP) ended up found to be significantly distinctive in athletes who necessary considerably less or more than fourteen days to return. When further research is necessary, the final results of this study are an critical move towards the development of a take a look at that could assist forecast which athletes want more time to recover from a concussion and resume exercise.

This study was released in JAMA Community Open up.


NINR Performing Scientific Director and study author Jessica M. Gill, Ph.D., R.N., FAAN is available for remark.


CL Pattinson et al. Plasma Biomarker Concentrations Linked with Return to Activity Subsequent Activity-Relevant Concussion in Collegiate Athletes – A Concussion Evaluation, Investigate, and Education and learning (Treatment) Consortium Examine. JAMA Community Open up. 20203(eight):e2013191. doi:ten.1001/jamanetworkopen.2020.13191

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